河北纖維素的溶液處于低溫時，大分子上的親水基團和水分子之間存在氫鍵效果，為水分子圍住而構成籠狀布局。溫度升高所施加的熱量將會使得水分子和羥丙基甲基纖維素分子之間的氫鍵開裂，籠狀的超分子布局被損壞，水分子從氫鍵效果的捆綁下釋放出來變成自在水分子，而羥丙基甲基纖維素大分子鏈上的疏水的甲氧基基團則露出出來，這就使得疏水聯系變成可能。溫度進一步升高，結尾一切的氫鍵都開裂，其疏水聯系到達最大程度，疏水聚集體的數量和尺度也隨之添加。在此過程中，羥丙基甲基纖維素使用規模愈加廣泛。爾后，不一樣的疏水聚集體之間經過疏水效果開端發作聯系。當溫度升高到凝膠點時，疏水聚集體構成的三維網絡布局充溢系統，微觀上表現為凝膠的構成。

 When a solution of hydroxypropyl methyl cellulose at a low temperature, between hydrophilic group and water molecule hydrogen bonds on the macromolecules, which is surrounded by water molecules form a cage. The temperature of heat applied will be such that the water molecules and the hydrogen bonds between the molecules of hydroxypropylmethylcellulose, cage-like supramolecular structure is damaged, the water molecules are released from the effect of the hydrogen bound to become free water molecules and the hydrophobic methoxy group of hydroxypropyl methylcellulose on the macromolecular chains is exposed, which makes it possible to hydrophobic binding. The temperature is further increased, eventually all hydrogen bonds break, the maximum degree of hydrophobic binding, number and size of the hydrophobic aggregates increases. In this process, hydroxypropyl methyl cellulose wider range of applications. Thereafter, different binding hydrophobic aggregates began by hydrophobic interaction. When the temperature rises to the gel point, the three-dimensional network structure formed by the hydrophobic aggregates full system performance for the formation of macroscopic gel.